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@article{f954245cc5b247b8a6cb031899720c0a,
title = "Drug use, depression and sexual risk behaviour: a syndemic among early pre-exposure prophylaxis (PrEP) adopters in Belgium?",
abstract = "Little is known about how interacting psychosocial problems may influence sexual behaviour among men having sex with men taking Pre-exposure prophylaxis (PrEP). This study assessed (1) the prevalence of depression, recreational drug-use and sexual risk behaviour; (2) changes in these psychosocial conditions over time; and (3) the interaction of drug use and depression with sexual risk behaviour. We analysed data of the Belgian Be-PrEP-ared cohort study (N = 200). We assessed depression using the PHQ-9, recreational drug use and receptive condomless anal intercourse (rCAI) with anonymous partners. Frequencies of psychosocial problems were compared at baseline, 9 and 18 months follow-up (FU). Bivariate associations between depression and drug-use behaviour, and their interaction with rCAI with anonymous sexual partners using was examined using linear regression. Receptive CAI increased from 41{\%} at baseline to 53{\%} at M18 (p = 0.038). At baseline, we found an interaction effect of poly-drug use and depression, potentiating rCAI with anonymous partners. Participants reporting poly-drug use associated with depression were significant more likely to report this type of sexual risk behaviour than those who did not report this association (p = 0.030). The high level of intertwined psychosocial problems call for multi-level interventions for those PrEP users experiencing a syndemic burden.",
keywords = "Adult, Belgium/epidemiology, Cohort Studies, Depression/epidemiology, HIV Infections/epidemiology, Homosexuality, Male/psychology, Humans, Male, Middle Aged, Pre-Exposure Prophylaxis, Prevalence, Risk-Taking, Sexual Behavior/psychology, Sexual Partners/psychology, Substance-Related Disorders/epidemiology, Syndemic, Unsafe Sex/statistics & numerical data, Young Adult",
author = "Christiana N{\"o}stlinger and Thijs Reyniers and Tom Smekens and Hanne Apers and Marie Laga and Kristien Wouters and Bea Vuylsteke",
note = "CPDF",
year = "2020",
doi = "10.1080/09540121.2020.1739218",
language = "English",
volume = "32",
pages = "57--64",
journal = "AIDS Care",
issn = "0954-0121",
publisher = "Routledge",
number = "Suppl.2",

}

RIS

TY - JOUR

T1 - Drug use, depression and sexual risk behaviour: a syndemic among early pre-exposure prophylaxis (PrEP) adopters in Belgium?

AU - Nöstlinger, Christiana

AU - Reyniers, Thijs

AU - Smekens, Tom

AU - Apers, Hanne

AU - Laga, Marie

AU - Wouters, Kristien

AU - Vuylsteke, Bea

N1 - CPDF

PY - 2020

Y1 - 2020

N2 - Little is known about how interacting psychosocial problems may influence sexual behaviour among men having sex with men taking Pre-exposure prophylaxis (PrEP). This study assessed (1) the prevalence of depression, recreational drug-use and sexual risk behaviour; (2) changes in these psychosocial conditions over time; and (3) the interaction of drug use and depression with sexual risk behaviour. We analysed data of the Belgian Be-PrEP-ared cohort study (N = 200). We assessed depression using the PHQ-9, recreational drug use and receptive condomless anal intercourse (rCAI) with anonymous partners. Frequencies of psychosocial problems were compared at baseline, 9 and 18 months follow-up (FU). Bivariate associations between depression and drug-use behaviour, and their interaction with rCAI with anonymous sexual partners using was examined using linear regression. Receptive CAI increased from 41% at baseline to 53% at M18 (p = 0.038). At baseline, we found an interaction effect of poly-drug use and depression, potentiating rCAI with anonymous partners. Participants reporting poly-drug use associated with depression were significant more likely to report this type of sexual risk behaviour than those who did not report this association (p = 0.030). The high level of intertwined psychosocial problems call for multi-level interventions for those PrEP users experiencing a syndemic burden.

AB - Little is known about how interacting psychosocial problems may influence sexual behaviour among men having sex with men taking Pre-exposure prophylaxis (PrEP). This study assessed (1) the prevalence of depression, recreational drug-use and sexual risk behaviour; (2) changes in these psychosocial conditions over time; and (3) the interaction of drug use and depression with sexual risk behaviour. We analysed data of the Belgian Be-PrEP-ared cohort study (N = 200). We assessed depression using the PHQ-9, recreational drug use and receptive condomless anal intercourse (rCAI) with anonymous partners. Frequencies of psychosocial problems were compared at baseline, 9 and 18 months follow-up (FU). Bivariate associations between depression and drug-use behaviour, and their interaction with rCAI with anonymous sexual partners using was examined using linear regression. Receptive CAI increased from 41% at baseline to 53% at M18 (p = 0.038). At baseline, we found an interaction effect of poly-drug use and depression, potentiating rCAI with anonymous partners. Participants reporting poly-drug use associated with depression were significant more likely to report this type of sexual risk behaviour than those who did not report this association (p = 0.030). The high level of intertwined psychosocial problems call for multi-level interventions for those PrEP users experiencing a syndemic burden.

KW - Adult

KW - Belgium/epidemiology

KW - Cohort Studies

KW - Depression/epidemiology

KW - HIV Infections/epidemiology

KW - Homosexuality, Male/psychology

KW - Humans

KW - Male

KW - Middle Aged

KW - Pre-Exposure Prophylaxis

KW - Prevalence

KW - Risk-Taking

KW - Sexual Behavior/psychology

KW - Sexual Partners/psychology

KW - Substance-Related Disorders/epidemiology

KW - Syndemic

KW - Unsafe Sex/statistics & numerical data

KW - Young Adult

U2 - 10.1080/09540121.2020.1739218

DO - 10.1080/09540121.2020.1739218

M3 - A1: Web of Science-article

C2 - 32160759

VL - 32

SP - 57

EP - 64

JO - AIDS Care

JF - AIDS Care

SN - 0954-0121

IS - Suppl.2

ER -

ID: 3312226