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Disseminated histoplasmosis: case report and review of the literature. / Evrard, Severine; Caprasse, Philippe; Gavage, Pierre; Vasbien, Myriam; Radermacher, Jean; Hayette, Marie-Pierre; Sacheli, Rosalie; Van Esbroeck, Marjan; Cnops, Lieselotte; Firre, Eric; Medart, Laurent; Moerman, Filip; Minon, Jean-Marc.

In: Acta Clinica Belgica, Vol. 73, Nr. 5, 2018, blz. 356-363.

Onderzoeksoutput: Bijdrage aan tijdschriftA1: Web of Science-artikel

Harvard

Evrard, S, Caprasse, P, Gavage, P, Vasbien, M, Radermacher, J, Hayette, M-P, Sacheli, R, Van Esbroeck, M, Cnops, L, Firre, E, Medart, L, Moerman, F & Minon, J-M 2018, 'Disseminated histoplasmosis: case report and review of the literature', Acta Clinica Belgica, vol. 73, nr. 5, blz. 356-363. https://doi.org/10.1080/17843286.2017.1376454

APA

Evrard, S., Caprasse, P., Gavage, P., Vasbien, M., Radermacher, J., Hayette, M-P., ... Minon, J-M. (2018). Disseminated histoplasmosis: case report and review of the literature. Acta Clinica Belgica, 73(5), 356-363. https://doi.org/10.1080/17843286.2017.1376454

Vancouver

Evrard S, Caprasse P, Gavage P, Vasbien M, Radermacher J, Hayette M-P et al. Disseminated histoplasmosis: case report and review of the literature. Acta Clinica Belgica. 2018;73(5):356-363. https://doi.org/10.1080/17843286.2017.1376454

Author

Evrard, Severine ; Caprasse, Philippe ; Gavage, Pierre ; Vasbien, Myriam ; Radermacher, Jean ; Hayette, Marie-Pierre ; Sacheli, Rosalie ; Van Esbroeck, Marjan ; Cnops, Lieselotte ; Firre, Eric ; Medart, Laurent ; Moerman, Filip ; Minon, Jean-Marc. / Disseminated histoplasmosis: case report and review of the literature. In: Acta Clinica Belgica. 2018 ; Vol. 73, Nr. 5. blz. 356-363.

BibTeX

@article{d6cf23c7eac64276bb7bd357a22326af,
title = "Disseminated histoplasmosis: case report and review of the literature",
abstract = "Case report We report the case of a young Cameroonian woman who presented with cough, hyperthermia, weight loss, pancytopenia, and hepatosplenomegaly. A positive HIV serology was discovered and a chest radiography revealed a miliary pattern'. Bone marrow aspiration pointed out yeast inclusions within macrophages. Given the morphological aspect, the clinical presentation and immunosuppression, histoplasmosis was retained as a working hypothesis. Antiretroviral and amphotericin B treatments were promptly initiated.Review Given the immigration wave that Europe is currently experiencing, we think it is important to share experience and knowledge, especially in non-endemic areas such as Europe, where clinicians are not used to face this disease. Histoplasmosis is due to Histoplasma capsulatum var. capsulatum, a dimorphic fungus. Infection occurs by inhaling spores contained in soils contaminated by bat or bird droppings. The clinical presentation depends on the immune status of the host and the importance of inoculum, varying from asymptomatic to disseminated forms. AIDS patients are particularly susceptible to develop a severe disease. Antigen detection, molecular biology techniques, and microscopic examination are used to make a rapid diagnosis. However, antigen detection is not available in Europe and diagnosis needs a strong clinical suspicion in non-endemic areas. Because of suggestive imagery, clinicians might focus on tuberculosis. Our case illustrates the need for clinicians to take histoplasmosis in the differential diagnosis, depending on the context and the patient's past history.",
keywords = "Histoplasmosis, Pancytopenia, AIDS, Dimorphic fungus, Histoplasma capsulatum, PENICILLIUM-MARNEFFEI INFECTION, PROGRESSIVE DISSEMINATED HISTOPLASMOSIS, NEEDLE-ASPIRATION-CYTOLOGY, LINKED-IMMUNOSORBENT-ASSAY, IMMUNODEFICIENCY-SYNDROME, CAPSULATUM ANTIGENURIA, SYSTEMIC MYCOSES, AIDS PATIENTS, SKIN-LESIONS, CASE SERIES",
author = "Severine Evrard and Philippe Caprasse and Pierre Gavage and Myriam Vasbien and Jean Radermacher and Marie-Pierre Hayette and Rosalie Sacheli and {Van Esbroeck}, Marjan and Lieselotte Cnops and Eric Firre and Laurent Medart and Filip Moerman and Jean-Marc Minon",
note = "CPDF",
year = "2018",
doi = "10.1080/17843286.2017.1376454",
language = "English",
volume = "73",
pages = "356--363",
journal = "Acta Clinica Belgica",
issn = "0001-5512",
publisher = "Taylor & Francis",
number = "5",

}

RIS

TY - JOUR

T1 - Disseminated histoplasmosis: case report and review of the literature

AU - Evrard, Severine

AU - Caprasse, Philippe

AU - Gavage, Pierre

AU - Vasbien, Myriam

AU - Radermacher, Jean

AU - Hayette, Marie-Pierre

AU - Sacheli, Rosalie

AU - Van Esbroeck, Marjan

AU - Cnops, Lieselotte

AU - Firre, Eric

AU - Medart, Laurent

AU - Moerman, Filip

AU - Minon, Jean-Marc

N1 - CPDF

PY - 2018

Y1 - 2018

N2 - Case report We report the case of a young Cameroonian woman who presented with cough, hyperthermia, weight loss, pancytopenia, and hepatosplenomegaly. A positive HIV serology was discovered and a chest radiography revealed a miliary pattern'. Bone marrow aspiration pointed out yeast inclusions within macrophages. Given the morphological aspect, the clinical presentation and immunosuppression, histoplasmosis was retained as a working hypothesis. Antiretroviral and amphotericin B treatments were promptly initiated.Review Given the immigration wave that Europe is currently experiencing, we think it is important to share experience and knowledge, especially in non-endemic areas such as Europe, where clinicians are not used to face this disease. Histoplasmosis is due to Histoplasma capsulatum var. capsulatum, a dimorphic fungus. Infection occurs by inhaling spores contained in soils contaminated by bat or bird droppings. The clinical presentation depends on the immune status of the host and the importance of inoculum, varying from asymptomatic to disseminated forms. AIDS patients are particularly susceptible to develop a severe disease. Antigen detection, molecular biology techniques, and microscopic examination are used to make a rapid diagnosis. However, antigen detection is not available in Europe and diagnosis needs a strong clinical suspicion in non-endemic areas. Because of suggestive imagery, clinicians might focus on tuberculosis. Our case illustrates the need for clinicians to take histoplasmosis in the differential diagnosis, depending on the context and the patient's past history.

AB - Case report We report the case of a young Cameroonian woman who presented with cough, hyperthermia, weight loss, pancytopenia, and hepatosplenomegaly. A positive HIV serology was discovered and a chest radiography revealed a miliary pattern'. Bone marrow aspiration pointed out yeast inclusions within macrophages. Given the morphological aspect, the clinical presentation and immunosuppression, histoplasmosis was retained as a working hypothesis. Antiretroviral and amphotericin B treatments were promptly initiated.Review Given the immigration wave that Europe is currently experiencing, we think it is important to share experience and knowledge, especially in non-endemic areas such as Europe, where clinicians are not used to face this disease. Histoplasmosis is due to Histoplasma capsulatum var. capsulatum, a dimorphic fungus. Infection occurs by inhaling spores contained in soils contaminated by bat or bird droppings. The clinical presentation depends on the immune status of the host and the importance of inoculum, varying from asymptomatic to disseminated forms. AIDS patients are particularly susceptible to develop a severe disease. Antigen detection, molecular biology techniques, and microscopic examination are used to make a rapid diagnosis. However, antigen detection is not available in Europe and diagnosis needs a strong clinical suspicion in non-endemic areas. Because of suggestive imagery, clinicians might focus on tuberculosis. Our case illustrates the need for clinicians to take histoplasmosis in the differential diagnosis, depending on the context and the patient's past history.

KW - Histoplasmosis

KW - Pancytopenia

KW - AIDS

KW - Dimorphic fungus

KW - Histoplasma capsulatum

KW - PENICILLIUM-MARNEFFEI INFECTION

KW - PROGRESSIVE DISSEMINATED HISTOPLASMOSIS

KW - NEEDLE-ASPIRATION-CYTOLOGY

KW - LINKED-IMMUNOSORBENT-ASSAY

KW - IMMUNODEFICIENCY-SYNDROME

KW - CAPSULATUM ANTIGENURIA

KW - SYSTEMIC MYCOSES

KW - AIDS PATIENTS

KW - SKIN-LESIONS

KW - CASE SERIES

U2 - 10.1080/17843286.2017.1376454

DO - 10.1080/17843286.2017.1376454

M3 - A1: Web of Science-article

VL - 73

SP - 356

EP - 363

JO - Acta Clinica Belgica

JF - Acta Clinica Belgica

SN - 0001-5512

IS - 5

ER -

ID: 2693389