• Vanham, Guido (Promotor)
  • VERHASSELT, Bruno (Partner)
  • MOUTSCHEN, Michel (Partner)
  • BERNEMAN, Zwi (Partner)
  • VANDAMME, Anne-Mieke (Partner)
  • BERKHOUT, Ben (Partner)

Beschrijving

General

The effective inhibition of HIV replication targeting viral escape and resistance under immune and drug pressure.


Specific

In silico: to genotype HIV drug resistance interpretation and predict HIV evolution with applied and optimalized resistance algorithms and fitness models as bio-informatics tools.



In vitro: to study new therapeutic HIV targets, siRNA manipulation and gene therapy, and the induction of anti-HIV cellular immune responses using normal donor and patients' blood cells and viral strains.



In vivo: to test the experimental immunological in vitro findings on relevance and/or efficiency in a Trimera mouse HIV model.


AcroniemHIV Control
StatusVoltooid
Effectieve start/einddatum1/01/0731/03/12

ID: 1079679