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Lut Lynen

  • Hiv/Aids
!!Postal address:
Nationalestraat 155
2000
Antwerp
België

!!Email: LLynen@itg.be

!!Phone: +32(0)32476476

Onderzoeksexpertise

Lut Lynen graduated as a medical doctor in 1985 from the Catholic University of Leuven. Between 1986 and 1992 she worked for MSF Belgium in Chad, Sudan and Guinea. In 1997 she became a specialist in Internal Medicine at the University of Antwerp.

She worked for the Institute of Tropical Medicine (ITM) in Cambodia from 1999-2002, and in 2003 she joined the HIV team at the Institute of Tropical Medicine in Antwerp, as the head of the overseas unit, responsible for HIV research projects abroad. During this time she developed and coordinated the Short Course on Antiretroviral Therapy (SCART) and the Telemedicine distant support service for HIV physicians in the field.

Her field of interest is AIDS care in resource-limited settings, in particular HIV co-infections and Opportunistic Infections. She is a member of the WHO guideline development group on Opportunistic Infections and the author of the MSF AIDS care guidelines.

In July 2011 she became the head of the department of Clinical Sciences, and in November 2011 the head of the Unit Infectious Diseases & HIV/AIDS.

The unit has 1 postdoctoral fellow, 1 PhD student (Ermias Diro, Ethiopia, 'Approach for Better Visceral Leishmaniasis Control in HIV Patients: Secondary Prophylaxis and HAART Optimization'), and 4 research assistants.

Research

  • HIV co-infections (tuberculosis and visceral leishmaniasis)
  • Point of Care testing for HIV diagnosis and monitoring of treatment response
  • Diagnosis and management of MDR-TB
  • Clinical decision making
  • Models of care for HIV patients

Teaching

Links

Kwalificaties

Medical sciences, PhD, Universiteit Antwerpen

Arts, Katholieke Universiteit Leuven

Onderzoeksoutputs

Effect of reliance on Xpert MTB/RIF on time to treatment and multidrug-resistant tuberculosis treatment outcomes in Tanzania: a retrospective cohort study

Mollel, E., Lekule, I., Lynen, L. & Decroo, T., 26-feb-2019, In : International Health.

Performance of algorithms for tuberculosis active case finding in underserved high-prevalence settings in Cambodia: a cross-sectional study

Choun, K., Decroo, T., Mao, T. E., Lorent, N., Gerstel, L., Creswell, J., Codlin, A. J., Lynen, L. & Thai, S., 2019, In : Global Health Action. 12, 1, 8 blz., 1646024.

Time of administration of rabies immunoglobulins and adequacy of antibody response upon post-exposure prophylaxis: a descriptive retrospective study in Belgium

Soentjens, P., Croughs, M., Burm, C., Declerq, S., Clerinx, J., Maniewski, U., Van Den Broucke, S., Theunissen, C., Huits, R., Brosius, I., Florence, E., Kenyon, C., Van Griensven, J., Van Ierssel, S., Lynen, L., Balliauw, K., Van Gucht, S., Van Esbroeck, M., Vlieghe, E., Bottieau, E. & 1 anderenVan Herrewege, Y., 2019, In : Acta Clinica Belgica. blz. 1-7 7 blz.

Comment on: Effects of isoniazid resistance on TB treatment outcomes under programmatic conditions in a high-TB and -HIV setting: a prospective multicentre study

Decroo, T., Van Deun, A. & Lynen, L., 2018, In : Journal of Antimicrobial Chemotherapy. 73, 6, blz. 1733-1734 2 blz.

Development of a clinical prediction score for targeted hepatitis C screening in a low-risk HIV cohort in Cambodia

De Weggheleire, A., Buyze, J., An, S., Thai, S., van Griensven, J., Francque, S. & Lynen, L., 2018, In : Journal of Hepatology. 68, blz. S177-S178 2 blz.

Prednisone for the prevention of paradoxical tuberculosis-associated IRIS

PredART Trial Team, 2018, In : New England Journal of Medicine. 379, 20, blz. 1915-1925 11 blz.

Principles for constructing a tuberculosis treatment regimen: the role and definition of core and companion drugs

Van Deun, A., Decroo, T., Piubello, A., de Jong, B. C., Lynen, L. & Rieder, H. L., 2018, In : International Journal of Tuberculosis and Lung Disease. 22, 3, blz. 239-245 8 blz.

The immune mechanisms of lung parenchymal damage in tuberculosis and the role of host-directed therapy

Stek, C., Allwood, B., Walker, N. F., Wilkinson, R. J., Lynen, L. & Meintjes, G., 2018, In : Frontiers in Microbiology. 9, 16 blz., 2603.

What is the role of paired rapid plasma reagin testing (simultaneous testing of acute and convalescent samples) in the diagnosis of repeat syphilis and the follow-up of syphilis?

Kenyon, C., Osbak, K., Lynen, L., Van Esbroeck, M. & Crucitti, T., 2018, In : Sexually transmitted diseases. 45, 1, blz. 35-38 4 blz.

A cross-sectional study of hepatitis C among people living with HIV in Cambodia: prevalence, risk factors, and potential for targeted screening

De Weggheleire, A., An, S., De Baetselier, I., Soeung, P., Keath, H., So, V., Ros, S., Teav, S., Smekens, B., Buyze, J., Florence, E., van Griensven, J., Thai, S., Francque, S. & Lynen, L., 2017, In : PLoS ONE. 12, 8, blz. e0183530 15 blz.

CD4 results with a bias larger than hundred cells per microliter can have a significant impact on the clinical decision during treatment initiation of HIV patients

Daneau, G., Buyze, J., Wade, D., Diaw, P. A., Dieye, T. N., Thai, S., Florence, E., Lynen, L. & Kestens, L., 2017, In : Cytometry Part B Clinical Cytometry. 92, 6, blz. 476-484 9 blz.

Development and external validation of a clinical prognostic score for death in visceral leishmaniasis patients in a high HIV co-infection burden area in Ethiopia

Abongomera, C., Ritmeijer, K., Vogt, F., Buyze, J., Mekonnen, Z., Admassu, H., Colebunders, R., Mohammed, R., Lynen, L., Diro, E. & van Griensven, J., 2017, In : PLoS ONE. 12, 6, blz. e0178996 17 blz.

Diagnosis of visceral leishmaniasis using peripheral blood microscopy in Ethiopia: a prospective phase-III study of the diagnostic performance of different concentration techniques compared to tissue aspiration

Diro, E., Yansouni, C., Takele, Y., Mengesha, B., Lynen, L., Hailu, A., van Griensven, J., Boelaert, M. & Büscher, P., 2017, In : American Journal of Tropical Medicine and Hygiene. 96, 1, blz. 190-196 7 blz.

Performance of the Antiretroviral Treatment Program in Ethiopia, 2005-2015: strengths and weaknesses toward ending AIDS

Assefa, Y., Gilks, C. F., Lynen, L., Williams, O., Hill, P. S., Tolera, T., Malvia, A. & Van Damme, W., 2017, In : International Journal of Infectious Diseases. 60, blz. 70-76 7 blz.

Rational use of Xpert testing in patients with presumptive TB: clinicians should be encouraged to use the test-treat threshold

Decroo, T., Henríquez-Trujillo, A. R., De Weggheleire, A. & Lynen, L., 2017, In : BMC Infectious Diseases. 17, blz. 674 6 blz.

Ten year experience with antiretroviral treatment in Cambodia: trends in patient characteristics and treatment outcomes

Lay, P., An, S., Soeung, S., Srey, P. S., Thai, S., Lynen, L. & Griensven, J. V., 2017, In : PLoS ONE. 12, 11, blz. e0185348 16 blz.

Unexpected infection with Armillifer parasites

Potters, I., Desaive, C., Van Den Broucke, S., Van Esbroeck, M. & Lynen, L., 2017, In : Emerging Infectious Diseases. 23, 12, blz. 2116-2118 3 blz.

Design and analysis considerations in the Ebola_Tx trial evaluating convalescent plasma in the treatment of Ebola virus disease in Guinea during the 2014-2015 outbreak

Edwards, T., Semple, M. G., De Weggheleire, A., Claeys, Y., De Crop, M., Menten, J., Ravinetto, R., Temmerman, S., Lynen, L., Bah, E. I., Smith, P. G., van Griensven, J. & Ebola_Tx Consortium, 2016, In : Clinical Trials. blz. 1-9

Electrolyte and metabolic disturbances in Ebola patients during a clinical trial, Guinea, 2015

van Griensven, J., Bah, E. I., Haba, N., Delamou, A., Camara, B. S., Olivier, K. J-J., De Clerck, H., Nordenstedt, H., Semple, M. G., Van Herp, M., Buyze, J., De Crop, M., Van Den Broucke, S., Lynen, L., De Weggheleire, A. & Ebola-Tx Consortium, 2016, In : Emerging Infectious Diseases. 22, 12, blz. 2120-2127 8 blz.

Evaluation of convalescent plasma for Ebola virus disease in Guinea

van Griensven, J., Edwards, T., de Lamballerie, X., Semple, M. G., Gallian, P., Baize, S., Horby, P. W., Raoul, H., Magassouba, NF., Antierens, A., Lomas, C., Faye, O., Sall, A. A., Fransen, K., Buyze, J., Ravinetto, R., Tiberghien, P., Claeys, Y., De Crop, M., Lynen, L. & 6 anderenBah, E. I., Smith, P. G., Delamou, A., De Weggheleire, A., Haba, N. & Ebola-Tx Consortium, 2016, In : New England Journal of Medicine. 374, 1, blz. 33-42 10 blz.

Factors associated with prevalent tuberculosis among patients receiving highly active antiretroviral therapy in a Nigerian tertiary hospital

Iroezindu, M. O., Ofondu, E. O., Mbata, G. C., van Wyk, B., Hausler, H. P., Dh, A., Lynen, L. & Hopewell, P. C., 2016, In : Annals of Medical and Health Sciences Research. 6, 2, blz. 120-128 9 blz.

Organizing the donation of convalescent plasma for a therapeutic clinical trial on Ebola virus disease: the experience in Guinea

Delamou, A., Haba, N. Y., Mari Saez, A., Galliant, P., Ronse, M., Jacobs, J., Camara, B. S., Kadio, K. J-J. O., Guemou, A., Kolie, J. P., De Crop, M., Chavarin, P., Jacquot, C., Lazaygues, C., Weggheleire, A. D., Lynen, L., van Griensven, J. & Ebola-Tx Consortium, 2016, In : American Journal of Tropical Medicine and Hygiene. 95, 3, blz. 647-653 7 blz.

Predictable threats to public health through delaying universal access to innovative medicines for Hepatitis C: a pharmaceutical standpoint

Ravinetto, R., Weggheleire, A. D., Dorlo, T. P. C., Francque, S., Sokkab, A., Pouget, C., Meessen, B., Tabernero, P., Newton, P. N. & Lynen, L., 2016, In : Tropical Medicine and International Health. 21, 12, blz. 1490-1495 12 blz.

Preventing paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome in high-risk patients: protocol of a randomized placebo-controlled trial of prednisone (predART trial)

Stek, C., Schutz, C., Blumenthal, L., Thienemann, F., Buyze, J., Nöstlinger, C., Ravinetto, R., Wouters, E., Colebunders, R., Maartens, G., Wilkinson, R. J., Lynen, L. & Meintjes, G., 2016, In : JMIR Research Protocols. 5, 3, blz. e173 13 blz.

The use of Ebola convalescent plasma to treat Ebola virus disease in resource-constrained settings: a perspective from the field

van Griensven, J., De Weggheleire, A., Delamou, A., Smith, P. G., Edwards, T., Vandekerckhove, P., Bah, E. I., Colebunders, R., Herve, I., Lazaygues, C., Haba, N. & Lynen, L., 2016, In : Clinical Infectious Diseases. 62, 1, blz. 69-74 6 blz.

Advanced HIV disease at enrolment in HIV care: trends and associated factors over a ten year period in Cambodia

Pe, R., Chim, B., Thai, S., Lynen, L. & van Griensven, J., 2015, In : PLoS ONE. 10, 11, blz. e0143320 11 blz.

Atypical manifestations of visceral leishmaniasis in patients with HIV in north Ethiopia: a gap in guidelines for the management of opportunistic infections in resource poor settings

Diro, E., van Griensven, J., Mohammed, R., Colebunders, R., Asefa, M., Hailu, A. & Lynen, L., 2015, In : Lancet Infectious Diseases. 15, 1, blz. 122-129 8 blz.

Challenges from tuberculosis diagnosis to care in community-based active case finding among the urban poor in Cambodia: a mixed-methods study

Lorent, N., Choun, K., Malhotra, S., Koeut, P., Thai, S., Khun, K. E., Colebunders, R. & Lynen, L., 2015, In : PLoS ONE. 10, 7, blz. e0130179 15 blz.

Clinical aspects of paediatric visceral leishmaniasis in north-west Ethiopia

Diro, E., Lynen, L., Gebregziabiher, B., Assefa, A., Lakew, W., Belew, Z., Hailu, A., Boelaert, M. & van Griensven, J., 2015, In : Tropical Medicine and International Health. 20, 1, blz. 8-16 9 blz.

Impact of the use of a rapid diagnostic test for visceral leishmaniasis on clinical practice in ethiopia: a retrospective study

Diro, E., Lynen, L., Assefa, M., Takele, Y., Mengesha, B., Adem, E., Mohammed, R., Kimutai, R., Hailu, A., Boelaert, M. & van Griensven, J., 2015, In : PLoS Neglected Tropical Diseases. 9, 5, blz. e0003738

Implementation of isoniazid preventive therapy in an HIV clinic in Cambodia: high rates of discontinuation when combined with antiretroviral therapy

van Griensven, J., Choun, K., Chim, B., Thai, S., Lorent, N. & Lynen, L., 2015, In : Tropical Medicine and International Health. 20, 12, blz. 1823-1831 7 blz.

Is frontloaded sputum microscopy an option in active tuberculosis case finding?

Lorent, N., Buyze, J., Kim, T., Kong, C., Van Deun, A., Colebunders, R., Thai, S., Lynen, L. & Rigouts, L., 2015, In : International Journal of Tuberculosis and Lung Disease. 19, 1, blz. 91-96 6 blz.

Long-term outcomes and their determinants in patients on antiretroviral treatment in Ethiopia, 2005/6-2011/12: a retrospective cohort study

Assefa, Y., Lynen, L., Kloos, H., Hill, P., Rasschaert, F., Hailemariam, D., Neilsen, G. & Van Damme, W., 2015, In : Journal of Acquired Immune Deficiency Syndromes. 70, 4, blz. 414-419 6 blz.

Systematic screening for drug-resistant tuberculosis with Xpert(®) MTB/RIF in a referral hospital in Cambodia

Lorent, N., Kong, C., Kim, T., Sam, S., Thai, S., Colebunders, R., Rigouts, L. & Lynen, L., 2015, In : International Journal of Tuberculosis and Lung Disease. 19, 12, blz. 1528-1535 11 blz.

Use of pentamidine as secondary prophylaxis to prevent visceral leishmaniasis relapse in HIV infected patients, the first twelve months of a prospective cohort study

Diro Ejara, E., Ritmeijer, K., Boelaert, M., Alves, F., Mohammed, R., Abongomera, C., Ravinetto, R., De Crop, M., Fikre, H., Adera, C., Colebunders, R., van Loen, H., Menten, J., Lynen, L., Hailu, A. & van Griensven, J., 2015, In : PLoS Neglected Tropical Diseases. 9, 10, blz. e0004087 15 blz.

A clinical prediction score for targeted creatinine testing before initiating tenofovir-based antiretroviral treatment in Cambodia [letter]

van Griensven, J., Phirum, L., Thai, S., Buyze, J. & Lynen, L., 2014, In : Journal of Acquired Immune Deficiency Syndromes. 65, 4, blz. e150-e152

A screen-and-treat strategy targeting visceral leishmaniasis in HIV-infected individuals in endemic East African countries: the way forward?

van Griensven, J., Diro, E., Lopez-Velez, R., Ritmeijer, K., Boelaert, M., Zijlstra, E. E., Hailu, A. & Lynen, L., 2014, In : PLoS Neglected Tropical Diseases. 8, 8, blz. e3011

Active tuberculosis screening of close contacts among the urban poor: a Cambodian experience [letter]

Lorent, N., Choun, K., Thai, S., Rigouts, L. & Lynen, L., 2014, In : International Journal of Tuberculosis and Lung Disease. 18, 10, blz. 1259-1260 2 blz.

Bacterial sepsis in patients with visceral leishmaniasis in Northwest Ethiopia

Endris, M., Takele, Y., Woldeyohannes, D., Tiruneh, M., Mohammed, R., Moges, F., Lynen, L., Jacobs, J., van Griensven, J. & Diro, E., 2014, In : BioMed Research International. 2014, blz. 361058

Community-based active tuberculosis case finding in poor urban settlements of Phnom Penh, Cambodia: a feasible and effective strategy

Lorent, N., Choun, K., Thai, S., Kim, T., Huy, S., Pe, R., van Griensven, J., Buyze, J., Colebunders, R., Rigouts, L. & Lynen, L., 2014, In : PLoS ONE. 9, 3, blz. e92754

Hepatitis B and C co-infection among HIV-infected adults while on antiretroviral treatment: long-term survival, CD4 cell count recovery and antiretroviral toxicity in Cambodia

van Griensven, J., Phirum, L., Choun, K., Thai, S., De Weggheleire, A. & Lynen, L., 2014, In : PLoS ONE. 9, 2, blz. e88552

High parasitological failure rate of visceral leishmaniasis to sodium stibogluconate among HIV co-infected adults in Ethiopia

Diro, E., Lynen, L., Mohammed, R., Boelaert, M., Hailu, A. & van Griensven, J., 2014, In : PLoS Neglected Tropical Diseases. 8, 5, blz. e2875

How to improve patient retention in an antiretroviral treatment program in Ethiopia: a mixed-methods study

Assefa, Y., Lynen, L., Wouters, E., Rasschaert, F., Peeters, K. & Van Damme, W., 2014, In : BMC Health Services Research. 14, blz. 45

Leishmaniasis in immunosuppressed individuals

van Griensven, J., Carrillo, E., López-Vélez, R., Lynen, L. & Moreno, J., 2014, In : Clinical Microbiology and Infection. 20, 4, blz. 286-299 14 blz.

Scaling up antiretroviral treatment and improving patient retention in care: lessons from Ethiopia, 2005-2013

Assefa, Y., Alebachew, A., Lera, M., Lynen, L., Wouters, E. & Van Damme, W., 2014, In : Globalization and Health. 10, blz. 43

Simplified clinical prediction scores to target viral load testing in adults with suspected first line treatment failure in Phnom Penh, Cambodia

van Griensven, J., Phan, V., Thai, S., Koole, O. & Lynen, L., 2014, In : PLoS ONE. 9, 2, blz. e87879

Syphilis reinfections pose problems for syphilis diagnosis in Antwerp, Belgium - 1992 to 2012

Kenyon, C., Lynen, L., Florence, E., Caluwaerts, S., Vandenbruaene, M., Apers, L., Soentjens, P., Van Esbroeck, M. & Bottieau, E., 2014, In : Eurosurveillance. 19, 45, blz. pii=20958

Visceral leishmaniasis and HIV coinfection in East Africa

Diro, E., Lynen, L., Ritmeijer, K., Boelaert, M., Hailu, A. & van Griensven, J., 2014, In : PLoS Neglected Tropical Diseases. 8, 6, blz. e2869

Visceral leishmaniasis as an AIDS defining condition: towards consistency across WHO guidelines

van Griensven, J., Ritmeijer, K., Lynen, L. & Diro, E., 2014, In : PLoS Neglected Tropical Diseases. 8, 7, blz. e2916

Bloodstream infection among adults in Phnom Penh, Cambodia: key pathogens and resistance patterns

Vlieghe, E. R., Phe, T., De Smet, B., Veng, C. H., Kham, C., Lim, K., Koole, O., Lynen, L., Peetermans, W. E. & Jacobs, J. A., 2013, In : PLoS ONE. 8, 3, blz. e59775

Evidence based medicine in HIV/AIDS and reproductive health research: piloting two distance learning courses in low-resource settings

Zolfo, M., Ingelbeen, B., Aryeetey, R., Cuzin-Kihl, A. K., Kiyan, C., Khanna, J., Maojo, V. & Lynen, L., 2013, Med@Tel, electronic proceedings of the international ehealth, telemedicine and health ICT forum for educational, networking and business, Luxembourg, 10-12 April 2013. Jordanova, M. & Lievens, F. (eds.). Luxembourg: International Society for Telemedicine and eHealth (ISfTeH), blz. 669-672 4 blz.

Evidence based medicine in HIV/AIDS and reproductive health research: piloting two distance learning courses in low-resource settings

Zolfo, M., Ingelbeen, B., Aryeetey, R., Cuzin-Kihl, A. K., Kiyan Tsunami, C., Khanna, J., Maojo, V., Lynen, L. & Group, A. B. WP., 2013, In : Global Telemedicine and eHealth Updates: Knowledge Resources. 6, blz. 669-672 4 blz.

HIV-1 protease inhibitors for treatment of visceral leishmaniasis in HIV-co-infected individuals

van Griensven, J., Diro, E., Lopez-Velez, R., Boelaert, M., Lynen, L., Zijlstra, E., Dujardin, J. C. & Hailu, A., 2013, In : Lancet Infectious Diseases. 13, 3, blz. 251-259 9 blz.

Incidence and risk factors for tuberculosis in HIV-infected patients while on antiretroviral treatment in Cambodia

Choun, K., Thai, S., Pe, R., Lorent, N., Lynen, L. & van Griensven, J., 2013, In : Transactions of the Royal Society of Tropical Medicine and Hygiene. 107, 4, blz. 235-242 8 blz.

Integrated cryptococcal antigen screening and pre-emptive treatment prior to initiation of antiretroviral treatment in Cambodia

Chim, B., Piseth, S. S., Heng, V. C., Sopheak, T., Lynen, L. & van Griensven, J., 2013, In : Aids and Clinical Research. 4, 7, blz. 1-6 6 blz.

Nucleoside reverse transcriptase inhibitor resistance mutations associated with first-line Stavudine-containing antiretroviral therapy: programmatic implications for countries phasing out stavudine

Tang, M. W., Rhee, S. Y., Bertagnolio, S., Ford, N., Holmes, S., Sigaloff, K. C., Hamers, R. L., Rinke de Wit, T. F., Fleury, H. J., Kanki, P. J., Ruxrungtham, K., Hawkins, C. A., Wallis, C. L., Stevens, W., van Zyl, G. U., Manosuthi, W., Hosseinipour, M. C., Ngo-Giang-Huong, N., Belec, L., Peeters, M. & 30 anderenAghokeng, A., Bunupuradah, T., Burdah, S., Cane, P., Cappelli, G., Charpentier, C., Dagnra, A. Y., Deshpande, A. K., El-Katib, Z., Eshleman, S. H., Fokam, J., Gody, J. C., Katzenstein, D., Koyalta, D. D., Kumwenda, J. J., Lallemant, M., Lynen, L., Marconi, V. C., Margot, N. A., Moussa, S., Ndung'u, T., Nyambi, P. N., Orrell, C., Schapiro, J. M., Schuurman, R., Sirivichayakul, S., Smith, D., Zolfo, M., Jordan, M. R. & Shafer, R. W., 2013, In : Journal of Infectious Diseases. 207, S2, blz. S70-S77

Rapid diagnostic tests for neurological infections in central Africa

Yansouni, C. P., Bottieau, E., Lutumba, P., Winkler, A. S., Lynen, L., Büscher, P., Jacobs, J., Gillet, P., Lejon, V., Alirol, E., Polman, K., Utzinger, J., Miles, M. A., Peeling, R. W., Muyembe, J. J., Chappuis, F. & Boelaert, M., 2013, In : Lancet Infectious Diseases. 13, 6, blz. 546-558 13 blz.

Risk factors of treatment-limiting anemia after substitution of zidovudine for stavudine in HIV-infected adult patients on antiretroviral treatment

Phe, T., Thai, S., Veng, C., Sok, S., Lynen, L. & van Griensven, J., 2013, In : PLoS ONE. 8, 3, blz. e60206

Timing of antiretroviral therapy in Cambodian hospital after diagnosis of tuberculosis: impact of revised WHO guidelines

Choun, K., Pe, R., Thai, S., Lorent, N., Lynen, L. & van Griensven, J., 2013, In : Bulletin of the World Health Organization. 91, 3, blz. 195-206 12 blz.

Validation of a clinical prediction score to target viral load testing in adults with suspected first line treatment failure in resource-constrained settings

Phan, V., Thai, S., Koole, O., Menten, J., Meheus, F., van Griensven, J. & Lynen, L., 2013, In : Journal of Acquired Immune Deficiency Syndromes. 62, 5, blz. 509-516 8 blz.

Staphylococcus aureus blood stream infections in Cambodian adults

Vlieghe, E., Phe, T., Hallin, M., Denis, O., Deplano, A., De Smet, B., Veng, C., Kham, C., Lynen, L., Peetermans, W. & Jacobs, J., jun-2012, In : International Journal of Infectious Diseases. blz. E437-E437

A clinical prediction score in addition to WHO criteria for anti-retroviral treatment failure in resource-limited settings - experience from Lesotho

Labhardt, N. D., Lejone, T., Setoko, M., Poka, M., Ehmer, J., Pfeiffer, K., Kiuvu, P. Z. & Lynen, L., 2012, In : PLoS ONE. 7, 10, blz. e47937

Adoption of new HIV treatment guidelines and drug substitutions within first-line as a measure of quality of care in rural Lesotho: health centers and hospitals compared

Labhardt, N. D., Sello, M., Lejone, T., Ehmer, J., Mokhantso, M., Lynen, L. & Pfeiffer, K., 2012, In : Tropical Medicine and International Health. 17, 10, blz. 1245-1254 10 blz.

Antiretroviral treatment in low-resource settings: what has changed in the last 10 years and what needs to change in the coming years?

Mehta, M., Semitala, F., Lynen, L. & Colebunders, R., 2012, In : Expert Review of Anti-infective Therapy. 10, 11, blz. 1287-1296 10 blz.

Azithromycin and ciprofloxacin resistance in Salmonella bloodstream infections in Cambodian adults

Vlieghe, E. R., Phe, T., De Smet, B., Veng, C. H., Kham, C., Bertrand, S., Vanhoof, R., Lynen, L., Peetermans, W. E. & Jacobs, J. A., 2012, In : PLoS Neglected Tropical Diseases. 6, 12, blz. e1933

Incidence of treatment-limiting toxicity with Stavudine-based antiretroviral therapy in Cambodia: a retrospective cohort study

Phan, V., Thai, S., Choun, K., Lynen, L. & van Griensven, J., 2012, In : PLoS ONE. 7, 1, blz. e30647

Is increasing complexity of algorithms the price for higher accuracy? Virtual comparison of three algorithms for tertiary level management of chronic cough in people living with HIV in a low-income country

Mukabatsinda, C., Nguyen, J., Bisig, B., Lynen, L., Coppens, YD., Asiimwe, A. & Van den Ende, J., 2012, In : BMC Medical Informatics and Decision Making. 12, blz. 2 10 blz.

Moodle report: the cornerstone between teaching activities and students' performance: Med@Tel, electronic proceedings of the international ehealth, telemedicine and health ICT forum for educational, networking and business, Luxembourg, 18-20 April 2012

Kiyan Tsunami, C., Zolfo, M., Mehta, M., Rasschaert, F. & Lynen, L., 2012, Med@Tel, electronic proceedings of the international ehealth, telemedicine and health ICT forum for educational, networking and business, Luxembourg, 18-20 April 2012. Jordanova, M. & Lievens, F. (eds.). Luxembourg: International Society for Telemedicine and eHealth (ISfTeH), 3 blz.

Nontuberculous mycobacterial disease in patients with HIV in Southeast Asia

McCarthy, K. D., Cain, K. P., Winthrop, K. L., Udomsantisuk, N., Lan, N. T. N., Sar, B., Kimerling, M., Kanara, N., Lynen, L., Monkongdee, P., Tasaneeyapan, T. & Varma, J. K., 2012, In : American Journal of Respiratory and Critical Care Medicine. 185, 9, blz. 981-8 8 blz.

Pretreatment HIV-1 drug resistance testing in sub-Saharan Africa [letter]

Lynen, L., Fransen, K., van Griensven, J. & Colebunders, R., 2012, In : Lancet Infectious Diseases. 12, 12, blz. 911 1 blz.

Short and long term retention in antiretroviral care in health facilities in rural Malawi and Zimbabwe

Rasschaert, F., Koole, O., Zachariah, R., Lynen, L., Manzi, M. & Van Damme, W., 2012, In : BMC Health Services Research. 12, blz. 444 12 blz.

A telemedicine service for HIV/AIDS physicians working in developing countries

Zolfo, M., Bateganya, MH., Adetifa, IM., Colebunders, R. & Lynen, L., 2011, In : Journal of Telemedicine and Telecare. 17, 2, blz. 65-70 6 blz.

Challenges in developing national HIV guidelines: experience from the eastern Mediterranean

De Weggheleire, A., Bortolotti, V., Zolfo, M., Crowley, S., Colebunders, R., Riedner, G. & Lynen, L., 2011, In : Bulletin of the World Health Organization. 89, 6, blz. 442-450 9 blz.

Determination of kidney function before tenofovir initiation: four-fold difference in need of tenofovir dose reduction depending on method used [letter]

van Griensven, J., Sopheak, T., Koole, O., Verpooten, GA. & Lynen, L., 2011, In : Journal of Acquired Immune Deficiency Syndromes. 57, 2, blz. e21-e23 3 blz.

Development and validation of systems for rational use of viral load testing in adults receiving first-line ART in sub-Saharan Africa

Abouyannis, M., Menten, J., Kiragga, A., Lynen, L., Robertson, G., Castelnuovo, B., Manabe, YC., Reynolds, SJ. & Roberts, L., 2011, In : AIDS. 25, 13, blz. 1627-1635

Evaluation of the 2007 WHO guideline to improve the diagnosis of tuberculosis in ambulatory HIV-positive adults

Koole, O., Thai, S., Khun, KE., Pe, R., van Griensven, J., Apers, L., Van den Ende, J., Mao, TE. & Lynen, L., 2011, In : PLoS ONE. 6, 4, blz. e18502 10 blz.

Genotypic impact of prolonged detectable HIV-1 RNA viral load after HAART failure in a CRF01_AE infected cohort

Zolfo, M., Schapiro, JM., Phan, V., Koole, O., Thai, S., Vekemans, M., Fransen, K. & Lynen, L., 2011, In : AIDS Research and Human Retroviruses. 27, 7, blz. 727-735 9 blz.

Melioidosis, Phnom Penh, Cambodia

Vlieghe, E., Kruy, L., De Smet, B., Kham, C., Veng, CH., Phe, T., Koole, O., Thai, S., Lynen, L. & Jacobs, J., 2011, In : Emerging Infectious Diseases. 17, 7, blz. 1289-1292 4 blz.

Prevention of mother-to-child transmission of HIV and the health-related Millennium Development Goals: time for a public health approach [viewpoint]

Schouten, EJ., Jahn, A., Midiani, D., Makombe, SD., Mnthambala, A., Chirwa, Z., Harries, AD., van Oosterhout, JJ., Meguid, T., Ben-Smith, A., Zachariah, R., Lynen, L., Zolfo, M., Van Damme, W., Gilks, CF., Atun, R., Shawa, M. & Chimbwandira, F., 2011, In : Lancet. 378, 9787, blz. 282-284 3 blz.

Surrogate markers of antiretroviral efficacy

Elliott, JH., van Griensven, J., McMahon, J. & Lynen, L., 2011, Sexually transmitted infections; 2nd ed. Gupta, S. & Kumar, B. (eds.). New Delhi: Elsevier, blz. 826-830 5 blz.

Telemedicine in HIV/AIDS care: a users' satisfaction survey

Zolfo, M., Lorent, N., Bateganya, M., Kiyan, C., Lequarré, F., Koole, O. & Lynen, L., 2011, Med@Tel, the international educational and networking forum for ehealth, telemedicine and health ICT, Luxembourg, 14-16 April 2010. Jordanova, M. & Lievens, F. (eds.). Luxembourg: International Society for Telemedicine and eHealth (ISfTeH), blz. 325-328 4 blz. (Global Telemedicine and eHealth Updates: Knowledge Resources; 3).

Attrition of HIV-infected individuals not yet eligible for antiretroviral treatment: do we care? [letter]

van Griensven, J., Sopheak, T., Aseffa, Y., Van Damme, W. & Lynen, L., 2010, In : Transactions of the Royal Society of Tropical Medicine and Hygiene. 104, 10, blz. 690-693 4 blz.

Challenges in HIV and visceral Leishmania co-infection: future research directions [letter]

Ejara, ED., Lynen, L., Boelaert, M. & van Griensven, J., 2010, In : Tropical Medicine and International Health. 15, 10, blz. 1266-1267 2 blz.

Challenges in the diagnosis of meningitis in low-resource settings [letter]

Yansouni, CP., Lynen, L. & Colebunders, R., 2010, In : Tropical Medicine and International Health. 15, 12, blz. 1556-1557 2 blz.

Combination therapy for visceral leishmaniasis

van Griensven, J., Balasegaram, M., Meheus, F., Alvar, J., Lynen, L. & Boelaert, M., 2010, In : Lancet Infectious Diseases. 10, 3, blz. 184-194 11 blz.

Decrease of vitamin D concentration in patients with HIV infection on a Non Nucleoside Reverse Transcriptase Inhibitor containing regimen

Conesa-Botella, A., Florence, E., Lynen, L., Colebunders, R., Menten, J. & Moreno-Reyes, R., 2010, In : Aids Research and Therapy. 7, 40, blz. 1-6 6 blz.

Mobile learning for HIV/AIDS healthcare worker training in resource-limited settings

Zolfo, M., Iglesias, D., Kiyan, C., Echevarria, J., Fucay, L., Llacsahuanga, E., de Waard, I., Suarez, V., Llaque, WL. & Lynen, L., 2010, In : Aids Research and Therapy. 7, 35, blz. 1-6 6 blz.

Monitoring for treatment failure in patients on first-line antiretroviral treatment in resource-constrained settings

Lynen, L., van Griensven, J. & Elliott, J., 2010, In : Current Opinion in HIV and AIDS. 5, 1, blz. 1-5 5 blz.

Performance of abdominal ultrasound for diagnosis of tuberculosis in HIV-infected persons living in Cambodia

Sculier, D., Vannarith, C., Pe, R., Thai, S., Kanara, N., Borann, S., Cain, KP., Lynen, L. & Varma, JK., 2010, In : Journal of Acquired Immune Deficiency Syndromes. 55, 4, blz. 500-502 3 blz.

Prevalence of chronic renal failure stage 3 of more in HIV-infected patients in Antwerp: an observational study

Colson, AW., Florence, E., Augustijn, H., Verpooten, GA., Lynen, L. & Gheuens, E., 2010, In : Acta Clinica Belgica. 65, 6, blz. 392-398 7 blz.

Time for 'test and treat' in prevention of mother-to-child transmission programs in low- and middle-income countries

Zolfo, M., De Weggheleire, A., Schouten, E. & Lynen, L., 2010, In : Journal of Acquired Immune Deficiency Syndromes. 55, 3, blz. 287-289 3 blz.

Treating HIV infection with drugs for HSV-2 infection? [authors' reply]

Buvé, A. & Lynen, L., 2010, In : Lancet. 376, 9735, blz. 88 1 blz.

Treating HIV infection with drugs for HSV-2 infection? [comment]

Buvé, A. & Lynen, L., 2010, In : Lancet. 375, 9717, blz. 782-784 3 blz.

Use of antiretroviral therapy in low- and middle-income countries

Elliott, J. (ed.), Lynen, L. (ed.) & Schapiro, JM. (ed.), 2010, In : Current Opinion in HIV and AIDS. 5, 1, blz. 1-5 109 blz.

An algorithm to optimize viral load testing in HIV-positive patients with suspected first-line antiretroviral therapy failure in Cambodia

Lynen, L., An, S., Koole, O., Thai, S., Ros, S., De Munter, P., Sculier, D., Arnould, L., Fransen, K., Menten, J., Boelaert, M., Van den Ende, J. & Colebunders, R., 2009, In : Journal of Acquired Immune Deficiency Syndromes. 52, 1, blz. 40-48 9 blz.

Challenges of HIV care in low-income countries; experience from a pilot project in Cambodia 2003-2007

Lynen, L., 2009, Antwerpen: Universiteit Antwerpen, Faculteit Geneeskunde; Antwerpen: Instituut voor Tropische Geneeskunde, Departement Klinische Wetenschappen. 168 blz.

Five-year experience with scaling-up access to antiretroviral treatment in an HIV care programme in Cambodia

Thai, S., Koole, O., Un, P., Ros, S., De Munter, P., Van Damme, W., Jacques, G., Colebunders, R. & Lynen, L., 2009, In : Tropical Medicine and International Health. 14, 9, blz. 1048-1058 11 blz.

Gastrointestinal conditions in people living with HIV

De Ryck, I., Ros, S., Lynen, L. & Colebunders, R., 2009, From the ground up: building comprehensive HIV/AIDS care programs in resource-limited settings. Volume 2: Establishing a framework for success. Marlink, RG. & Teitelman, SJ. (eds.). [Washington D.C.]: Elizabeth Glaser Pediatric AIDS Foundation, blz. 277-296 20 blz.

Is vitamin D deficiency involved in the immune reconstitution inflammatory syndrome?

Conesa-Botella, A., Mathieu, C., Colebunders, R., Moreno-Reyes, R., van Etten, E., Lynen, L. & Kestens, L., 2009, In : Aids Research and Therapy. 6, 4, blz. 1-5 5 blz.

Substituting nevirapine for efavirenz: risk factors for toxicity in nonnaive patients in a resource-constrained setting [correspondence]

van Griensven, J., Un, P., Phe, T., Thai, S. & Lynen, L., 2009, In : AIDS. 23, 17, blz. 2374-2376

Substituting tenofovir for stavudine in resource-limited settings: there are challenges ahead [correspondence]

van Griensven, J., Lynen, L. & Colebunders, R., 2009, In : AIDS. 23, 8, blz. 1027

Telemedicine in low-resource settings: experience with a telemedicine service for HIV/AIDS care

Zolfo, M., Renggli, V., Koole, O. & Lynen, L., 2009, Telehealth in the developing world. Wootton, R., Patil, NG., Scott, RE. & Ho, K. (eds.). Ottawa: International Development Research Centre (IDRC); London: Royal Society of Medicine Press, blz. 91-100 10 blz.

Fever after a stay in the tropics: clinical spectrum and outcome in HIV-infected travelers and migrants

Bottieau, E., Florence, E., Clerinx, J., Vlieghe, E., Vekemans, M., Moerman, F., Lynen, L., Colebunders, R., Van Gompel, A. & Van den Ende, J., 2008, In : Journal of Acquired Immune Deficiency Syndromes. 48, 5, blz. 547-552 6 blz.

Predictors of CD4+ cell count response and of adverse outcome among HIV-infected patients receiving highly active antiretroviral therapy in a public hospital in Peru

López-de Castilla, D., Verdonck, K., Otero, L., Iglesias, D., Echevarria, J., Lynen, L., Gotuzzo, E. & Seas, C., 2008, In : International Journal of Infectious Diseases. 12, 3, blz. 325-331 7 blz.

Prevention and treatment of the immune reconstitution inflammatory syndrome

Meintjes, G. & Lynen, L., 2008, In : Current Opinion in HIV and AIDS. 3, 4, blz. 468-476 9 blz.

Rational use of antiretroviral therapy in low-income and middle-income countries: optimizing regimen sequencing and switching

Elliott, JH., Lynen, L., Calmy, A., De Luca, A., Shafer, RW., Zolfo, M., Clotet, B., Huffam, S., Boucher, CAB., Cooper, DA. & Schapiro, JM., 2008, In : AIDS. 22, 16, blz. 2053-2067 15 blz.

Tuberculosis-associated immune reconstitution inflammatory syndrome: case definitions for use in resource-limited settings

Meintjes, G., Lawn, SD., Scano, F., Maartens, G., French, MA., Worodria, W., Elliott, JH., Murdoch, D., Wilkinson, RJ., Seyler, C., John, L., Schim van der Loeff, M., Reiss, P., Lynen, L., Janoff, EN., Gilks, C. & Colebunders, R., 2008, In : Lancet Infectious Diseases. 8, 8, blz. 516-523 8 blz.

Bridging the gap between clinical practice and diagnostic clinical epidemiology: pilot experiences with a didactic model based on a logarithmic scale

Van den Ende, J., Bisoffi, Z., Van Puymbroeck, H., Van der Stuyft, P., Van Gompel, A., Derese, A., Lynen, L., Moreira, J. & Janssen, PAJ., 2007, In : Journal of Evaluation in Clinical Practice. 13, 3, blz. 374-380

Co-trimoxazole prophylaxis in tropical countries in the era of highly active antiretroviral therapy: do we know enough?

Lynen, L., Jacobs, J. & Colebunders, R., 2007, In : Transactions of the Royal Society of Tropical Medicine and Hygiene. 101, 11, blz. 1059-1060

HIV viral load monitoring in resource-limited regions: optional or necessary?

Calmy, A., Ford, N., Hirschel, B., Reynolds, SJ., Lynen, L., Goemaere, E., Garcia de la Vega, F., Perrin, L. & Rodriguez, W., 2007, In : Clinical Infectious Diseases. 44, 1, blz. 128-134

Immune reconstitution inflammatory syndrome in an HIV/TB co-infected patient four years after starting antiretroviral therapy

Huyst, V., Lynen, L., Bottieau, E., Zolfo, M., Kestens, L. & Colebunders, R., 2007, In : Acta Clinica Belgica. 62, 2, blz. 126-129

Opportunistic infections and HIV clinical disease stage among patients presenting for care in Phnom Penh, Cambodia

Kong, BN., Harwell, JI., Suos, P., Lynen, L., Mohiuddin, S., Reinert, S. & Pugatch, D., 2007, In : Southeast Asian Journal of Tropical Medicine and Public Health. 38, 1, blz. 1-7

[Evaluating a model for monitoring the virological efficacy of antiretroviral treatment in resource-limited settings] [reply]

Colebunders, R., Lynen, L., Meya, D., Reynolds, S. & Moses, K., 2006, In : Lancet Infectious Diseases. 6, 7, blz. 387-388

A new model to monitor the virological efficacy of antiretroviral treatment in resource-poor countries

Colebunders, R., Moses, KR., Laurence, J., Shihab, HM., Semitala, F., Lutwama, F., Bakeera-Kitaka, S., Lynen, L., Spacek, L., Reynolds, SJ., Quinn, TC., Viner, B. & Mayanja-Kizza, H., 2006, In : Lancet Infectious Diseases. 6, 1, blz. 53-59

AIDS in the Rift Valley region

Colebunders, R., Callens, S., Huyst, V., Zolfo, M., Ponnet, M. & Lynen, L., 2006, Africa's great rift: diversity and unity; international conference, Brussels, 29-30 September, 2005. De Dapper, M. & de Lame, D. (eds.). Tervuren: Koninklijk Museum voor Midden-Afrika / Musée Royal de l'Afrique Centrale; Brussel: Koninklijke Academie voor Overzeese Wetenschappen / Académie Royale des Sciences d'Outre-Mer (ARSOM), blz. 249-262

Clinical HIV/AIDS care guidelines for resource-poor settings; 2nd ed

Lynen, L., 2006, Brussels: Médecins Sans Frontières (MSF). 346 blz.

Demographic and clinical characteristics of HIV-infected inpatients and outpatients at a Cambodian hospital

Sok, P., Harwell, JI., McGarvey, ST., Lurie, M., Lynen, L., Flanigan, T. & Mayer, KH., 2006, In : AIDS Patient Care and STDs. 20, 5, blz. 369-378

Early neuroschistosomiasis complicating Katayama syndrome [letter]

Clerinx, J., Van Gompel, A., Lynen, L. & Ceulemans, B., 2006, In : Emerging Infectious Diseases. 12, 9, blz. 1465-1466

Remote consultations and HIV/AIDS continuing education in low-resource settings

Zolfo, M., Lynen, L., Dierckx, J. & Colebunders, R., 2006, In : International Journal of Medical Informatics. 75, 9, blz. 633-637

The added value of a CD4 count to identify patients eligible for highly active antiretroviral therapy among HIV-positive adults in Cambodia

Lynen, L., Thai, S., De Munter, P., Leang, B., Sokkab, A., Schrooten, W., Huyst, V., Kestens, L., Jacques, G., Colebunders, R., Menten, J. & Van den Ende, J., 2006, In : Journal of Acquired Immune Deficiency Syndromes. 42, 3, blz. 322-324

Tuberculosis immune reconstitution inflammatory syndrome in countries with limited resources

Colebunders, R., John, L., Huyst, V., Kambugu, A., Scano, F. & Lynen, L., 2006, In : International Journal of Tuberculosis and Lung Disease. 10, 9, blz. 946-953

Validation of primary CD4 gating as an affordable strategy for absolute CD4 counting in Cambodia

Lynen, L., Teav, S., Vereecken, C., DE MUNTER, PAUL., An, S., Jacques, G. & Kestens, L., 2006, In : Journal of Acquired Immune Deficiency Syndromes. 43, 2, blz. 179-185

Comparison of albendazole regimen for prophylaxis of strongyloides hyperinfection in nephrotic syndrome patients on long-term steroids in Cambodia

Leang, B., Lynen, L., Schrooten, W. & Hines, J., 2005, In : Tropical Doctor. 35, 4, blz. 212-213

Management of kaposi's sarcoma in resource-limited settings in the era of HAART

Lynen, L., Zolfo, M., Huyst, V., Barnardt, P., Van de Velde, A., De Schacht, C. & Colebunders, R., 2005, In : AIDS Reviews. 7, blz. 13-21

Palliative care in sub-Saharan Africa [letter]

Colebunders, R., John, L., Muganzi, A., Lynen, L. & Kambugu, A., 2005, In : Lancet. 366, 9485, blz. 546-547

Persistent galactorrhea in a postmenopausal woman with herpes zoster and HIV-1 infection

Bateganya, MH., Muhwezi, J., Mugyenyi, P., Kityo, C., Lynen, L., Zolfo, M. & Colebunders, R., 2005, In : Malawi Medical Journal. 17, blz. 100-101

Prevention of tuberculosis in resource-poor countries with increasing access to highly active antiretroviral treatment [review editorial]

Apers, L., Lynen, L., Worodria, W. & Colebunders, R., 2005, In : Tropical Medicine and International Health. 10, 12, blz. 1209-1214

Severe dyshidrosis in two patients with HIV infection shortly after starting highly active antiretroviral treatment [letter]

Colebunders, R., Zolfo, M. & Lynen, L., 2005, In : Dermatology Online Journal. 11, 2, blz. 31 1 blz.

Telemedicine as a distance learning tool for HIV/AIDS care in low resource settings

Zolfo, M., Arnould, L., Huyst, V., De Munter, P., An, S., Bateganya, M. & Lynen, L., 2005, In : Journal on Information Technology in Healthcare. 3, blz. 173-178

Telemedicine for HIV/AIDS care in low resource settings

Zolfo, M., Arnould, L., Huyst, V. & Lynen, L., 2005, Medical and care compunetics 2. Bos, L., Laxminarayan, S. & Marsh, A. (eds.). Amsterdam: IOS Press, blz. 18-22 (Studies in Health Technology and Informatics; 114).

The first reported cases of disseminated histoplasmosis in Cambodia, complicated by multiple opportunistic infections

Bun Navy, K., Prem Prey, S., Lynen, L., Sovanna, P., Bell, JD. & Harwell, JI., 2005, In : Southeast Asian Journal of Tropical Medicine and Public Health. 36, blz. 1272-1274

Death caused by strongyloides hyperinfection in a leprosy patient on treatment for a type II leprosy reaction

Leang, B., Lynen, L., Tootill, R., Griffiths, S. & Monchy, D., 2004, In : Leprosy review. 75, blz. 398-403

Disseminated nocardiosis presenting with cardiac tamponade in an HIV patient

Leang, B., Lynen, L., Lim, K., Jacques, G., Van Esbroeck, M. & Zolfo, M., 2004, In : International Journal of STD & AIDS. 15, blz. 839-840

Highly active antiretroviral treatment in countries with very limited resources: do we have cheaper alternatives? [editorial]

Colebunders, R., Florence, E., Lynen, L. & Bouckenooghe, A., 2003, In : International Journal of STD & AIDS. 14, blz. 1-5

Do patents prevent access to drugs for HIV in developing countries? [letter]

Boelaert, M., Lynen, L., Van Damme, W. & Colebunders, R., 2002, In : Journal of the American Medical Association. 287, blz. 840-841

Patients with HIV infection and fever: a diagnostic approach

Florence, E., Bottieau, E., Lynen, L. & Colebunders, R., 2002, In : Acta Clinica Belgica. 57, blz. 184-190

Changing epidemiological and clinical aspects of imported malaria in Belgium

Van den Ende, J., Morales, I., Van den Abbeele, K., Clerinx, J., Colebunders, R., Kager, P., Lynen, L., Van Gompel, A., Van der Planken, M. & Vervoort, T., 2001, In : Journal of Travel Medicine. 8, 1, blz. 19-25

Clinical AIDS care guidelines for resource-poor settings

Lynen, L., 2001, Brussels: Médecins Sans Frontières (MSF).

Clinical and biological manifestations of dengue [letter]

Van den Ende, J. & Lynen, L., 1999, In : Tropical Medicine and International Health. 4, blz. 239-240

Cost-effectiveness of competing diagnostic-therapeutic strategies for visceral leishmaniasis

Boelaert, M., Lynen, L., Desjeux, P. & Van der Stuyft, P., 1999, In : Bulletin of the World Health Organization. 77, blz. 667-674

A cluster of airport malaria in Belgium in 1995

Van den Ende, J., Lynen, L., Elsen, P., Colebunders, R., Demey, H., Depraetere, K., De Schrijver, K., Peetermans, WE., Pereira de Almeida, P. & Vogelaers, D., 1998, In : Acta Clinica Belgica. 53, blz. 259-263

Evaluation of two tests based on the detection of histidine rich protein 2 for the diagnosis of imported Plasmodium falciparum malaria

Van den Ende, J., Vervoort, T., Van Gompel, A. & Lynen, L., 1998, In : Transactions of the Royal Society of Tropical Medicine and Hygiene. 92, blz. 285-288

Splenic rupture as a complication of P. falciparum malaria after residence in the tropics; report of two cases

De Aguirre, Z., De Droogh, E., Van den Ende, J., Lynen, L., Depraetere, K., Demey, HE., De Schepper, A., Hubens, G. & Colebunders, R., 1998, In : Acta Clinica Belgica. 53, blz. 374-377

Controverses in de behandeling van ernstige malaria

Lynen, L. & Van den Ende, J., 1997, Proceedings; Geneeskundige Dagen van Antwerpen 1997. [Antwerpen]: [s.n.]

Diagnosis of malaria disease

Van den Ende, J. & Lynen, L., 1997, Handbook of malaria infection in the tropics. Carosi, G. & Castelli, F. (eds.). Bologna: Associazione Italiana 'Amici di R. Follereau' (AIFO), blz. 137-150 (Quaderni di Cooperazione Sanitaria. Health Cooperation Papers. Cahiers de Cooperation Médicale; 15).

Measles vaccination and inflammatory bowel disease [letter]

Van Damme, W., Lynen, L., Kegels, G. & van Lerberghe, W., 1997, In : Lancet. 350, blz. 1774-1775

Clinical algorithm for malaria in Africa [letter]

Van den Ende, J., Van Gompel, A., Lynen, L. & Van Damme, W., 1996, In : Lancet. 347, blz. 1327

Local application of diminazene aceturate: an effective treatment for cutaneous leishmaniasis?

Lynen, L. & Van Damme, W., 1992, In : Annales de la Société Belge de Médecine Tropicale. 72, blz. 13-19

Projecten

Better clinical management of Visceral Leishmaniasis in HIV patients in Ethiopia: secondary prophylaxis and HAART optimization.

Ejara, E. D., Lynen, L., van Griensven, J., Colebunders, B. & Hailu, A.

1/03/1026/05/15

AFRICA BUILD: Building a research and education infrastructure for Africa

Lynen, L. & Baeten, E.

European Commission

1/08/1131/07/14

AfriCoLeish: Care package for treatment and control of visceral leishmaniasis in East Africa

Balasegaram, M., Ravinetto, R., van Griensven, J., Baeten, E., Alexander, N., Diro, E., Edwards, T., Ellis, S., Mudawi Musa, A., Ritmeijer, K., Wasunna, M., Yifru, S., Zijlstra, E., Lynen, L. & Sy, H.

European Commission

1/01/1331/12/16

Challenge for optimal care for people living with HIV in countries with limited resources: findings from observational studies from different settings.

Koole, O., Lynen, L., Colebunders, B. & Jaffar, S.

22/01/1529/05/15

Differentiated Implementation of HIV Treat All in Zimbabwe

Makurumidze, R., Lynen, L., Decroo, T., Van Damme, W., Hakim, J. & Rusakaniko, S.

1/03/18 → …

Early diagnosis and care of tuberculosis through community-based active case-finding using rapid diagnostic tests in urban slums of Phnom Penh, Cambodia

Lorent, N., Colebunders, R., Lynen, L., Rigouts, L. & Colebunders, B.

22/10/132/10/15

HEPATITIS C: Hepatitis C treatment for HIV patients in resource-poor countries: is a public health approach possible

Lynen, L., van Griensven, J., Florence, E. & Ratsarahery, L.

Flemish Government - Department of Economy, Science & Innovation

1/07/1431/12/19

Hepatitis C/HIV coinfection in Cambodia: from pilot project to lessons learned for a public health approach

De Weggheleire, A., Lynen, L. & Francque, S.

26/04/18 → …

CAMBODIA - 2018 - FA4: National Institutes in Cambodia have increased capacity to generate evidence for the management of health problems and for the strengthening of the health system in Cambodia.

Lynen, L., Jacobs, J., Rosanas-Urgell, A., De Baetselier, I., De Weggheleire, A., Smekens, B., Stassijns, J., Van Damme, W., van de Put, W., Delvaux, T. & Ratsarahery, L.

DGD

1/01/1831/12/18

PREDICT.VL: Predicting visceral leishmaniasis in HIV infected patients: how to screen and who to treat

van Griensven, J., Lynen, L. & Ratsarahery, L.

Flemish Government - Department of Economy, Science & Innovation

1/07/1430/06/19

PREDART: Preventing tuberculosis-associated immune reconstitution inflammatory syndrome in high-risk patients : a randomised placebo-controlled trial of prednisone

Meintjes, G., Colebunders, R., Baeten, E., Maartens, G., Wilkinson, R. J., Lynen, L. & Baeten, E.

European & Developing Countries Clinical Trials Partnership

1/12/1231/08/15

The immunomodulatory role of prednisone in TB-HIV co-infected patients and assessment of its impact on clinical and TB treatment outcomes

STEK, C., Lynen, L. & Meintjes, G.

30/04/15 → …

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