Mycobacteriologie

!!Postal address
Nationalestraat 155
2000
Antwerp
België
Contact

Telefoon: +32(0)32476590

Onderzoeksexpertise

Bouke de Jong graduated in Medicine in 1995 from the University of Amsterdam, in internal medicine at the University of Nevada at Reno in 2000, and in infectious diseases at Stanford University in 2003.

At Stanford University she worked on the molecular epidemiology of tuberculosis, which studies she extended to the MRC Laboratories in The Gambia in 2003. In 2005 she completed MSc studies in epidemiology at the Netherlands Institute for Health Sciences, and in 2007 defended her PhD entitled “Studies on Mycobacterium africanum in The Gambia” at the University of Amsterdam. In 2007, Dr. de Jong joined the Division of Infectious Diseases at New York University as a tenure track Assistant Professor, while continuing her studies in The Gambia. 

In 2010 Dr. de Jong was appointed as head of the Unit of Mycobacteriology at the Institute of Tropical Medicine. She now applies molecular epidemiology to study the impact of public health interventions to reduce TB transmission, supported by an ERC starting grant INTERRUPTB. She furthermore integrates her work on strain differences in West Africa, with research lines on Buruli Ulcer and TB drug resistance, and supporting the broader activities and goals of the Unit of Mycobacteriology.

Research lines

  • Strain differences between M. africanum and M. tuberculosis
  • Differences in the ex vivo transcriptome of M. tuberculosis in sputum between patients with and without HIV co-infection
  • Impact of enhanced case finding on TB transmission
  • Molecular mechanisms underlying TB drug resistance
  • Phylogeography of M. ulcerans
  • Differential diagnosis of Buruli Ulcer

Onderzoeksoutput

  1. The predominance of Ethiopian specific Mycobacterium tuberculosis families and minimal contribution of Mycobacterium bovis in tuberculous lymphadenitis patients in Southwest Ethiopia

    Onderzoeksoutput: Bijdrage voor tijdschriftA2: Artikel in een internationaal wetenschappelijk tijdschrift met peer review, dat niet inbegrepen is in A1

  2. Significant under expression of the DosR regulon in M. tuberculosis complex lineage 6 in sputum

    Onderzoeksoutput: Bijdrage voor tijdschriftA1: Web of Science-artikel

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