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Results from a cross-sectional sexual and reproductive health study among school girls in Tanzania: high prevalence of bacterial vaginosis. / Francis, Suzanna C.; Hansen, Christian Holm; Irani, Julia; Andreasen, Aura; Baisley, Kathy; Jespers, Vicky; Crucitti, Tania; Changalucha, John; Hayes, Richard J.; Nnko, Soori; Watson-Jones, Deborah; Buvé, Anne.

In: Sexually Transmitted Infections, Vol. 95, No. 3, 2019, p. 219-227.

Research output: Contribution to journalA1: Web of Science-article

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Francis, SC, Hansen, CH, Irani, J, Andreasen, A, Baisley, K, Jespers, V, Crucitti, T, Changalucha, J, Hayes, RJ, Nnko, S, Watson-Jones, D & Buvé, A 2019, 'Results from a cross-sectional sexual and reproductive health study among school girls in Tanzania: high prevalence of bacterial vaginosis', Sexually Transmitted Infections, vol. 95, no. 3, pp. 219-227. https://doi.org/10.1136/sextrans-2018-053680

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Francis, Suzanna C. ; Hansen, Christian Holm ; Irani, Julia ; Andreasen, Aura ; Baisley, Kathy ; Jespers, Vicky ; Crucitti, Tania ; Changalucha, John ; Hayes, Richard J. ; Nnko, Soori ; Watson-Jones, Deborah ; Buvé, Anne. / Results from a cross-sectional sexual and reproductive health study among school girls in Tanzania: high prevalence of bacterial vaginosis. In: Sexually Transmitted Infections. 2019 ; Vol. 95, No. 3. pp. 219-227.

BibTeX

@article{42ef03ae582744c0af7de543ef60eab5,
title = "Results from a cross-sectional sexual and reproductive health study among school girls in Tanzania: high prevalence of bacterial vaginosis",
abstract = "Objectives Bacterial vaginosis (BV) increases women's susceptibility to sexually transmitted infections (STIs) and HIV and may partly explain the high incidence of STI/HIV among girls and young women in East and southern Africa. The objectives of this study were to investigate the association between BV and sexual debut, to investigate other potential risk factors of BV and to estimate associations between BV and STIs.Methods Secondary school girls in Mwanza, aged 17 and 18 years, were invited to join a cross-sectional study. Consenting participants were interviewed and samples were obtained for STI and BV testing. Factors associated with prevalent BV were analysed using multivariable logistic regression. Y-chromosome was tested as a biomarker for unprotected penile-vaginal sex.Results Of the 386 girls who were enrolled, 163 (42{\%}) reported having ever had penile-vaginal sex. Ninety-five (25{\%}) girls had BV. The prevalence of BV was 33{\%} and 19{\%} among girls who reported or did not report having ever had penile-vaginal sex, respectively. BV was weakly associated with having ever had one sex partner (adjusted odds ratio (aOR) 1.59; 95{\%} CI 0.93 to 2.71) and strongly associated with two or more partners (aOR = 3.67; 95{\%} CI 1.75 to 7.72), receptive oral sex (aOR 6.38; 95{\%} CI 1.22 to 33.4) and having prevalent human papillomavirus infection (aOR = 1.73; 95{\%} CI 1.02 to 2.95). Of the 223 girls who reported no penile-vaginal sex, 12 (5{\%}) tested positive for an STI and 7 (3{\%}) tested positive for Y-chromosome. Reclassifying these positive participants as having ever had sex did not change the key results.Conclusions Tanzanian girls attending school had a high prevalence of BV. Increasing number of sex partner was associated with BV; however, 19{\%} of girls who reported no penile-vaginal sex had BV. This suggests that penile-vaginal sexual exposure may not be a prerequisite for BV. There was evidence of under-reporting of sexual debut.",
keywords = "Adolescent, Cross-Sectional Studies, Female, Humans, Incidence, Papillomavirus Infections/epidemiology, Prevalence, Reproductive Health, Risk Factors, Sexual Behavior, Students, Tanzania/epidemiology, Vaginosis, Bacterial/epidemiology",
author = "Francis, {Suzanna C.} and Hansen, {Christian Holm} and Julia Irani and Aura Andreasen and Kathy Baisley and Vicky Jespers and Tania Crucitti and John Changalucha and Hayes, {Richard J.} and Soori Nnko and Deborah Watson-Jones and Anne Buv{\'e}",
note = "{\circledC} Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY. Published by BMJ.",
year = "2019",
doi = "10.1136/sextrans-2018-053680",
language = "English",
volume = "95",
pages = "219--227",
journal = "Sexually Transmitted Infections",
issn = "1368-4973",
publisher = "BMJ Publishing Group",
number = "3",

}

RIS

TY - JOUR

T1 - Results from a cross-sectional sexual and reproductive health study among school girls in Tanzania: high prevalence of bacterial vaginosis

AU - Francis, Suzanna C.

AU - Hansen, Christian Holm

AU - Irani, Julia

AU - Andreasen, Aura

AU - Baisley, Kathy

AU - Jespers, Vicky

AU - Crucitti, Tania

AU - Changalucha, John

AU - Hayes, Richard J.

AU - Nnko, Soori

AU - Watson-Jones, Deborah

AU - Buvé, Anne

N1 - © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY. Published by BMJ.

PY - 2019

Y1 - 2019

N2 - Objectives Bacterial vaginosis (BV) increases women's susceptibility to sexually transmitted infections (STIs) and HIV and may partly explain the high incidence of STI/HIV among girls and young women in East and southern Africa. The objectives of this study were to investigate the association between BV and sexual debut, to investigate other potential risk factors of BV and to estimate associations between BV and STIs.Methods Secondary school girls in Mwanza, aged 17 and 18 years, were invited to join a cross-sectional study. Consenting participants were interviewed and samples were obtained for STI and BV testing. Factors associated with prevalent BV were analysed using multivariable logistic regression. Y-chromosome was tested as a biomarker for unprotected penile-vaginal sex.Results Of the 386 girls who were enrolled, 163 (42%) reported having ever had penile-vaginal sex. Ninety-five (25%) girls had BV. The prevalence of BV was 33% and 19% among girls who reported or did not report having ever had penile-vaginal sex, respectively. BV was weakly associated with having ever had one sex partner (adjusted odds ratio (aOR) 1.59; 95% CI 0.93 to 2.71) and strongly associated with two or more partners (aOR = 3.67; 95% CI 1.75 to 7.72), receptive oral sex (aOR 6.38; 95% CI 1.22 to 33.4) and having prevalent human papillomavirus infection (aOR = 1.73; 95% CI 1.02 to 2.95). Of the 223 girls who reported no penile-vaginal sex, 12 (5%) tested positive for an STI and 7 (3%) tested positive for Y-chromosome. Reclassifying these positive participants as having ever had sex did not change the key results.Conclusions Tanzanian girls attending school had a high prevalence of BV. Increasing number of sex partner was associated with BV; however, 19% of girls who reported no penile-vaginal sex had BV. This suggests that penile-vaginal sexual exposure may not be a prerequisite for BV. There was evidence of under-reporting of sexual debut.

AB - Objectives Bacterial vaginosis (BV) increases women's susceptibility to sexually transmitted infections (STIs) and HIV and may partly explain the high incidence of STI/HIV among girls and young women in East and southern Africa. The objectives of this study were to investigate the association between BV and sexual debut, to investigate other potential risk factors of BV and to estimate associations between BV and STIs.Methods Secondary school girls in Mwanza, aged 17 and 18 years, were invited to join a cross-sectional study. Consenting participants were interviewed and samples were obtained for STI and BV testing. Factors associated with prevalent BV were analysed using multivariable logistic regression. Y-chromosome was tested as a biomarker for unprotected penile-vaginal sex.Results Of the 386 girls who were enrolled, 163 (42%) reported having ever had penile-vaginal sex. Ninety-five (25%) girls had BV. The prevalence of BV was 33% and 19% among girls who reported or did not report having ever had penile-vaginal sex, respectively. BV was weakly associated with having ever had one sex partner (adjusted odds ratio (aOR) 1.59; 95% CI 0.93 to 2.71) and strongly associated with two or more partners (aOR = 3.67; 95% CI 1.75 to 7.72), receptive oral sex (aOR 6.38; 95% CI 1.22 to 33.4) and having prevalent human papillomavirus infection (aOR = 1.73; 95% CI 1.02 to 2.95). Of the 223 girls who reported no penile-vaginal sex, 12 (5%) tested positive for an STI and 7 (3%) tested positive for Y-chromosome. Reclassifying these positive participants as having ever had sex did not change the key results.Conclusions Tanzanian girls attending school had a high prevalence of BV. Increasing number of sex partner was associated with BV; however, 19% of girls who reported no penile-vaginal sex had BV. This suggests that penile-vaginal sexual exposure may not be a prerequisite for BV. There was evidence of under-reporting of sexual debut.

KW - Adolescent

KW - Cross-Sectional Studies

KW - Female

KW - Humans

KW - Incidence

KW - Papillomavirus Infections/epidemiology

KW - Prevalence

KW - Reproductive Health

KW - Risk Factors

KW - Sexual Behavior

KW - Students

KW - Tanzania/epidemiology

KW - Vaginosis, Bacterial/epidemiology

U2 - 10.1136/sextrans-2018-053680

DO - 10.1136/sextrans-2018-053680

M3 - A1: Web of Science-article

C2 - 30518620

VL - 95

SP - 219

EP - 227

JO - Sexually Transmitted Infections

JF - Sexually Transmitted Infections

SN - 1368-4973

IS - 3

ER -

ID: 2982543