DOI

  • Sheila Makiala
  • Daniel Mukadi
  • Anja De Weggheleire
  • Shino Muramatsu
  • Daisuke Kato
  • Koichi Inano
  • Fumio Gondaira
  • Masahiro Kajihara
  • Reiko Yoshida
  • Katendi Changula
  • Aaron Mweene
  • Placide Mbala-Kingebeni
  • Jean-Jacques Muyembe-Tamfum
  • Justin Masumu
  • Steve Ahuka
  • Ayato Takada

The recent large outbreaks of Ebola virus disease (EVD) in West Africa and the Democratic Republic of the Congo (DRC) have highlighted the need for rapid diagnostic tests to control this disease. In this study, we clinically evaluated a previously developed immunochromatography-based kit, QuickNavi(TM)-Ebola. During the 2018 outbreaks in DRC, 928 blood samples from EVD-suspected cases were tested with QuickNavi(TM)-Ebola and the WHO-approved GeneXpert. The sensitivity and specificity of QuickNavi(TM)-Ebola, estimated by comparing it to GeneXpert-confirmed cases, were 85% (68/80) and 99.8% (846/848), respectively. These results indicate the practical reliability of QuickNavi(TM)-Ebola for point-of-care diagnosis of EVD.

Original languageEnglish
Article number589
JournalViruses
Volume11
Issue number7
Number of pages7
ISSN1999-4915
DOIs
Publication statusPublished - 2019

Bibliographical note

CPDF

    Research areas

  • Ebola virus, EVD, rapid diagnostic test, immunochromatography, QuickNavi, DRC

ID: 3026931